Brad Pitt has a Leonardo Favio number of 4.

Brad Pitt
was in
The Assassination of Jesse James: Death of an Outlaw
with
Ted Levine
was in
Wild Wild West
with
Buck Taylor
was in
Triumphs of a Man Called Horse
with
Lautaro MurĂșa
was in
The Venerable Ones
with
Leonardo Favio